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Chronic Respiratory Disease, Vol. 5, No. 1, 7-11 (2008)
DOI: 10.1177/1479972307082329

Quality of life in patients with chronic obstructive pulmonary disease: the predictive validity of the BODE index

M. Medinas-Amorós

Department of Psychology, Joan March Hospital, Bunyola, Baleares, Spain, mmapsi{at}hotmail.com

C. Alorda

Department of Psychology, Joan March Hospital, Bunyola, Baleares, Spain

F. Renom

Department of Respiratory Medicine, Joan March Hospital, Bunyola, Baleares, Spain

M. Rubí

Department of Respiratory Medicine, Joan March Hospital, Bunyola, Baleares, Spain

J. Centeno

Department of Respiratory Medicine, Joan March Hospital, Bunyola, Baleares, Spain

V. Ferrer

Department of Psychology, University of Balearic Islands, Baleares, Spain

T. Gorriz

Department of Respiratory Medicine, Joan March Hospital, Bunyola, Baleares, Spain

C. Mas-Tous

Department of Psychology, University of Balearic Islands, Baleares, Spain

F. Ramis

Department of Respiratory Medicine, Joan March Hospital, Bunyola, Baleares, Spain

Background: Chronic obstructive pulmonary disease (COPD) is currently the fourth cause of mortality and morbility in the developed world. Patients with COPD experience a progressive deterioration of health-related quality of life (HRQOL). A new model of severity classification, the body mass index, bronchial obstruction, dyspnoea, exercise (BODE) index, has recently been proposed.

Objective: To evaluate the relationship between HRQOL and the BODE index, and the predictive ability of BODE on HRQOL measurements.

Methods: Two HRQOL questionnaires were administered, namely the Nottingham Health Profile (NHP) and St George's Respiratory Questionnaire (SGRQ), in a sample of 67 patients with severe COPD.

Results: Pearsons correlation coefficient analysis shows a positive correlation between the BODE index and the total scores of the specific (P < 0.001), and general HRQOL (P < 0.001); the analysis shows a significant correlation between the BODE index and the subscales of symptoms, activity and impact of SGRQ (P < 0.001) and the subscales energy and physical mobility of the NHP (P < 0.001). The regression analysis shows that the BODE index is a significant predictor of HRQOL, explaining 46,1% of the total score of the SGRQ (P < 0.001) and 14.8% of the total score of the NHP (P < 0.001).

Conclusions: The BODE index is good at predicting the worsening of HRQOL in patients with severe COPD. Chronic Respiratory Disease 2008; 5: 7—11

Key Words: COPD • dyspnoea • Nottingham Health Profile • quality of life • St Georgés Respiratory Questionnaire • walking test


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